Alzheimer’s Disease Research Study
If you or a loved one has been diagnosed with Alzheimer’s disease, a local research study may be an option.
This study is for adults ages 55 to 80 who are living with mild to moderate Alzheimer’s disease and have noticed changes in memory or thinking over the past year.
What is Alzheimer’s?
Alzheimer’s disease can affect memory, thinking, behavior, and daily activities. Researchers are studying an oral medication to see if it may help slow changes in memory and thinking in people with mild to moderate Alzheimer’s disease who test positive for P. gingivalis.
P. gingivalis is a bacteria commonly associated with gum disease. This study will help researchers better understand whether targeting this bacteria may play a role in Alzheimer’s disease research.
Eligible Participants Are:
- 55 to 80 years of age
- Diagnosed with probable Alzheimer’s disease
- Experiencing mild to moderate memory or thinking difficulties
- Showing signs of cognitive decline within the past year
- Able to complete memory and thinking assessments
Eligible Participants May:
- Receive study-related care at no cost to you
- Receive memory and thinking assessments
- Complete saliva testing for P. gingivalis
- Receive regular support from experienced research staff
- Receive compensation for study-related time and travel, if available
About This Study
Compensation
All study-related care and assessments are provided at no cost. Compensation for study related time may be available.
Time Commitment
Participation may last up to approximately 64 weeks. This includes a screening period, a 48-week study treatment period, and a 4-week safety follow-up period.
Locations
This study is currently enrolling at:
Study Focus
Researchers are evaluating the safety and effectiveness of an oral medication, compared with placebo in adults with mild to moderate Alzheimer’s disease who test positive for P. gingivalis.
Why Take Part?
Study participation may include:
- Study-related care at no cost
- Ongoing support from a dedicated research team
- Memory and thinking assessments
- Health and safety monitoring throughout the study
- Compensation for study-related time and travel, if available
Every volunteer moves research forward. By participating, you or your loved one may help advance Alzheimer’s disease research and contribute to a better understanding of how oral bacteria may be connected to memory and thinking changes.
Caregiver / Study Partner Requirement
Because Alzheimer’s disease can affect memory and daily functioning, each participant must have a caregiver or study partner who is willing to take part in the study process.
This person may be asked to:
- Attend clinic visits with the participant
- Help provide information about the participant’s memory and daily functioning
- Assist with study medication, if needed
- Help the study team understand any changes during participation
This caregiver involvement is an important part of determining whether the study may be a good fit.
What to Expect Next:
- Fill out the brief health questionnaire
- Speak with a member of our study team
- Review medical history, current medications, and Alzheimer’s diagnosis
- If the study may be a fit, schedule screening visits
- Complete study-related testing, which may include saliva testing, memory assessments, blood work, ECG, and brain imaging
The research team will guide you and your caregiver through each step.
